The resident of this home had lost her husband a few years earlier.
She has a strong interest in 'spirituality' and new age practices like Reiki.
This photo is from the upstairs hallway. It would not be surprising if this orb represents the spirit of her late husband.
When seen enlarged, this orb appears to have a 'face', with two eyes and a smiling mouth.
Photos from the same camera taken elsewhere in the home showed no 'orb' or other anomaly.